Characterization of a Novel MMS-Sensitive Allele of Schizosaccharomyces pombe mcm4+
The minichromosome maintenance (MCM) complex is the conserved helicase motor of the eukaryotic replication fork. Mutations in the Mcm4 subunit are associated with replication stress and double strand breaks in multiple systems. In this work, we characterize a new temperature-sensitive allele of Schi...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Oxford University Press
2016-10-01
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Series: | G3: Genes, Genomes, Genetics |
Subjects: | |
Online Access: | http://g3journal.org/lookup/doi/10.1534/g3.116.033571 |