Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection.

Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection.

Staphylococcus aureus is capable of infecting nearly every organ in the human body. In order to infiltrate and thrive in such diverse host tissues, staphylococci must possess remarkable flexibility in both metabolic and virulence programs. To investigate the genetic requirements for bacterial surviv...

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Bibliographic Details
Main Authors: Aimee D Wilde, Daniel J Snyder, Nicole E Putnam, Michael D Valentino, Neal D Hammer, Zachery R Lonergan, Scott A Hinger, Esar E Aysanoa, Catlyn Blanchard, Paul M Dunman, Gregory A Wasserman, John Chen, Bo Shopsin, Michael S Gilmore, Eric P Skaar, James E Cassat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4684308?pdf=render

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http://europepmc.org/articles/PMC4684308?pdf=render

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