The Therapeutic Effect of Curcumin in Quinolinic Acid-Induced Neurotoxicity in Rats is Associated with BDNF, ERK1/2, Nrf2, and Antioxidant Enzymes

In the present study we investigated the participation of brain-derived neurotropic factor (BDNF) on the activation of the mitogen activated protein kinase (MAPK) protein extracellular signal-regulated kinase-1/2 (ERK1/2) as a mechanism of curcumin (CUR) to provide an antioxidant defense system medi...

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Bibliographic Details
Main Authors: Ricardo A. Santana-Martínez, Carlos A. Silva-Islas, Yessica Y. Fernández-Orihuela, Diana Barrera-Oviedo, José Pedraza-Chaverri, Rogelio Hernández-Pando, Perla D. Maldonado
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/8/9/388