Cabozantinib in the treatment of advanced renal cell carcinoma in adults following prior vascular endothelial growth factor targeted therapy: clinical trial evidence and experience

Cabozantinib is an oral multitargeted tyrosine kinase inhibitor (TKI) that potently inhibits MET and AXL, both associated with poor prognosis in renal cell carcinoma (RCC), next to vascular endothelial growth factor receptor 2, KIT, FLT3 and RET. Chronic treatment with vascular endothelial growth fa...

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Bibliographic Details
Main Authors: Susanne Osanto, Tom van der Hulle
Format: Article
Language:English
Published: SAGE Publishing 2018-03-01
Series:Therapeutic Advances in Urology
Online Access:https://doi.org/10.1177/1756287217748867