Synergistic and complete reversal of the multidrug resistance of mitoxantrone hydrochloride by three-in-one multifunctional lipid-sodium glycocholate nanocarriers based on simultaneous BCRP and Bcl-2 inhibition

Guixia Ling,1 Tianhong Zhang,2 Peng Zhang,2 Jin Sun,1 Zhonggui He1 1Department of Pharmaceutics, 2Department of Pharmaceutical Analysis, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China Abstract: Multidrug resistance (MDR) is a severe obstacle...

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Bibliographic Details
Main Authors: Ling G, Zhang T, Zhang P, Sun J, He Z
Format: Article
Language:English
Published: Dove Medical Press 2016-08-01
Series:International Journal of Nanomedicine
Subjects:
Online Access:https://www.dovepress.com/synergistic-and-complete-reversal-of-the-multidrug-resistance-of-mitox-peer-reviewed-article-IJN