Administration of bovine anti-IGF-1 immunoglobulin to dietary protein deficient rats alters dietary intake and plasma IGF-1 binding profiles, but does not affect change in body mass

Administration of bovine anti-IGF-1 immunoglobulin to dietary protein deficient rats alters dietary intake and plasma IGF-1 binding profiles, but does not affect change in body mass

The potential of antibodies raised against insulin-like growth factor-1 (IGF-1) as a treatment to enhance the anabolic actions of IGF-1 has been demonstrated in both rodent and ruminant models. We investigated whether treatment of genetically normal rats with anti-IGF-1 immunoglobulin (Ig, raised in...

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Bibliographic Details
Main Authors: N.N. Smith, M.J. Kelly, J.M. Pell, R.A. Hill
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Animal
Subjects:
immunomodulation
IGF-1
catabolism
passive immunisation
Online Access:http://www.sciencedirect.com/science/article/pii/S1751731110000686

Internet

http://www.sciencedirect.com/science/article/pii/S1751731110000686

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