Macrophage Immune Response Suppression by Recombinant Mycobacterium tuberculosis Antigens, the ESAT-6, CFP-10, and ESAT-6/CFP-10 Fusion Proteins

Macrophage Immune Response Suppression by Recombinant Mycobacterium tuberculosis Antigens, the ESAT-6, CFP-10, and ESAT-6/CFP-10 Fusion Proteins

Background: Macrophage immune responses are affected by the secretory proteins of Mycobacterium tuberculosis (Mtb). This study aimed to examine the immune responses of macrophages to Mtb secretory antigens, namely ESAT-6, CFP-10, and ESAT-6/CFP-10. Methods: THP-1 cells (a human monocytic cell line)...

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Bibliographic Details
Main Authors: Atefeh Seghatoleslam, Mina Hemmati, Saeedeh Ebadat, Bahram Movahedi, Zohreh Mostafavi-Pour
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2016-07-01
Series:Iranian Journal of Medical Sciences
Subjects:
Mycobacterium Tuberculosis
Recombinant Proteins
ESAT-6 protein
CFP-10 protein
Reactive Oxygen Species
Online Access:http://ijms.sums.ac.ir/index.php/IJMS/article/view/2722

Internet

http://ijms.sums.ac.ir/index.php/IJMS/article/view/2722

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