Research Progress on PARP14 as a Drug Target

Research Progress on PARP14 as a Drug Target

Poly-adenosine diphosphate-ribose polymerase (PARP) implements posttranslational mono- or poly-ADP-ribosylation modification of target proteins. Among the known 18 members in the enormous family of PARP enzymes, several investigations about PARP1, PARP2, and PARP5a/5b have been launched in the past...

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Bibliographic Details
Main Authors: Wei Qin, Hong-Jie Wu, Lu-Qi Cao, Hui-Jin Li, Chun-Xia He, Dong Zhao, Lu Xing, Peng-Quan Li, Xi Jin, Hui-Ling Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Pharmacology
Subjects:
PARP14
drug target
cancer
atherosclerosis
allergic inflammation
molecular mechanism
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00172/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00172/full

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