Predictive Value of Precision-Cut Lung Slices for the Susceptibility of Three Animal Species for SARS-CoV-2 and Validation in a Refined Hamster Model

Predictive Value of Precision-Cut Lung Slices for the Susceptibility of Three Animal Species for SARS-CoV-2 and Validation in a Refined Hamster Model

In assessing species susceptibility for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and in the search for an appropriate animal model, multiple research groups around the world inoculated a broad range of animal species using various SARS-CoV-2 strains, doses and administration rou...

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Bibliographic Details
Main Authors: Nora M. Gerhards, Jan B. W. J. Cornelissen, Lucien J. M. van Keulen, José Harders-Westerveen, Rianka Vloet, Bregtje Smid, Stéphanie Vastenhouw, Sophie van Oort, Renate W. Hakze-van der Honing, Jose L. Gonzales, Norbert Stockhofe-Zurwieden, Rineke de Jong, Wim H. M. van der Poel, Sandra Vreman, Jeroen Kortekaas, Paul J. Wichgers Schreur, Nadia Oreshkova
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pathogens
Subjects:
SARS-CoV-2
hamster model
precision-cut lung slices
activity
histology scores
Online Access:https://www.mdpi.com/2076-0817/10/7/824

Internet

https://www.mdpi.com/2076-0817/10/7/824

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