miRNA-98-5p Targeting IGF2BP1 Induces Mesenchymal Stem Cell Apoptosis by Modulating PI3K/Akt and p53 in Immune Thrombocytopenia

miRNA-98-5p Targeting IGF2BP1 Induces Mesenchymal Stem Cell Apoptosis by Modulating PI3K/Akt and p53 in Immune Thrombocytopenia

Immune thrombocytopenia (ITP) is a common hematological autoimmune disease, in which defective mesenchymal stem cells (MSCs) are potentially involved. Our previous study suggested that MSCs in ITP patients displayed enhanced apoptosis. MicroRNAs (miRNAs) play important roles in ITP by affecting mega...

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Bibliographic Details
Main Authors: Yanan Wang, Jiamin Zhang, Yan Su, Chencong Wang, Gaochao Zhang, Xiao Liu, Qi Chen, Meng Lv, Yingjun Chang, Jun Peng, Ming Hou, Xiaojun Huang, Xiaohui Zhang
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120301219

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http://www.sciencedirect.com/science/article/pii/S2162253120301219

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