Insights into protease sequence similarities by comparing substrate sequences and phylogenetic dynamics

Insights into protease sequence similarities by comparing substrate sequences and phylogenetic dynamics

Based on substrate sequences, we proposed a novel method for comparing sequence similarities among 68 proteases compiled from the MEROPS online database. The rank vector was defined based on the frequencies of amino acids at each site of the substrate, aiming to eliminate the different order varianc...

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Bibliographic Details
Main Authors: Enfeng Qi, Can Fu, Ying Zhai, Jianghui Dong
Format: Article
Language:English
Published: AIMS Press 2021-04-01
Series:Mathematical Biosciences and Engineering
Subjects:
protease phylogeny
substrate sequences
phylogenetic tree
kegg
merops
homology
Online Access:http://www.aimspress.com/article/doi/10.3934/mbe.2021044?viewType=HTML

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http://www.aimspress.com/article/doi/10.3934/mbe.2021044?viewType=HTML

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