Molecular and Functional Profiles of Exosomes From HPV(+) and HPV(−) Head and Neck Cancer Cell Lines

Molecular and Functional Profiles of Exosomes From HPV(+) and HPV(−) Head and Neck Cancer Cell Lines

Exosomes produced by tumor cells have been shown to reprogram functions of human immune cells. Molecular cargos of exosomes isolated from supernatants of HPV(+) and HPV(−) head and neck cancer (HNC) cell lines or from HNC patients' plasma were compared. The exosome protein profiles resembled th...

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Bibliographic Details
Main Authors: Sonja Ludwig, Priyanka Sharma, Marie-Nicole Theodoraki, Monika Pietrowska, Saigopalakrishna S. Yerneni, Stephan Lang, Soldano Ferrone, Theresa L. Whiteside
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Oncology
Subjects:
exosomes
head and neck cancer
HPV(+) and HPV(−) tumor cells
protein profiling
immune functions
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00445/full

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https://www.frontiersin.org/article/10.3389/fonc.2018.00445/full

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