Conversion of adult human fibroblasts into neural precursor cells using chemically modified mRNA

Conversion of adult human fibroblasts into neural precursor cells using chemically modified mRNA

Direct reprogramming offers a unique approach by which to generate neural lineages for the study and treatment of neurological disorders. Our objective is to develop a clinically viable reprogramming strategy to generate neural precursor cells for the treatment of neurological disorders through cell...

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Bibliographic Details
Main Authors: Bronwen Connor, Erin Firmin, Amy McCaughey-Chapman, Ruth Monk, Kevin Lee, Sophie Liot, Johannes Geiger, Carsten Rudolph, Kathryn Jones
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Heliyon
Subjects:
Biotechnology
Neuroscience
Stem cell research
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844018327191

Internet

http://www.sciencedirect.com/science/article/pii/S2405844018327191

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