Assessment of Human Islet Labeling with Clinical Grade Iron Nanoparticles Prior to Transplantation for Graft Monitoring by MRI

Assessment of Human Islet Labeling with Clinical Grade Iron Nanoparticles Prior to Transplantation for Graft Monitoring by MRI

Ex vivo labeling of islets with superparamagnetic iron oxide (SPIO) nanoparticles allows posttransplant MRI imaging of the graft. In the present study, we compare two clinical grade SPIOs (ferucarbotran and ferumoxide) in terms of toxicity, islet cellular uptake, and MRI imaging. Human islets (80–90...

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Bibliographic Details
Main Authors: Frederic Ris M.D., Matthieu Lepetit-Coiffe, Paolo Meda, Lindsey A. Crowe, Christian Toso, Mathieu Armanet, Nadja Niclauss, Géraldine Parnaud, Laurianne Giovannoni, Domenico Bosco, Philippe Morel, Jean-Paul Vallee, Thierry Berney
Format: Article
Language:English
Published: SAGE Publishing 2010-12-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368910X515863

Internet

https://doi.org/10.3727/096368910X515863

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