Posttranscriptional Gene Regulatory Networks in Chronic Airway Inflammatory Diseases: In silico Mapping of RNA-Binding Protein Expression in Airway Epithelium

Posttranscriptional Gene Regulatory Networks in Chronic Airway Inflammatory Diseases: In silico Mapping of RNA-Binding Protein Expression in Airway Epithelium

Background: Posttranscriptional gene regulation (PTGR) contributes to inflammation through alterations in messenger RNA (mRNA) turnover and translation rates. RNA-binding proteins (RBPs) coordinate these processes but their role in lung inflammatory diseases is ill-defined. We evaluated the expressi...

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Bibliographic Details
Main Authors: Luca Ricciardi, Giorgio Giurato, Domenico Memoli, Mariagrazia Pietrafesa, Jessica Dal Col, Ilaria Salvato, Annunziata Nigro, Alessandro Vatrella, Gaetano Caramori, Vincenzo Casolaro, Cristiana Stellato
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
airway epithelium
chronic inflammation
COPD
posttranscriptional gene regulation
RNA binding proteins
severe asthma
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.579889/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.579889/full

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