Activation and inhibition of transglutaminase 2 in mice.

Transglutaminase 2 (TG2) is an allosterically regulated enzyme with transamidating, deamidating and cell signaling activities. It is thought to catalyze sequence-specific deamidation of dietary gluten peptides in the small intestines of celiac disease patients. Because this modification has profound...

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Bibliographic Details
Main Authors: Laila Dafik, Megan Albertelli, Jorunn Stamnaes, Ludvig M Sollid, Chaitan Khosla
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3271093?pdf=render