MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling.

MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling.

Mitochondrial calcium uptake is present in nearly all vertebrate tissues and is believed to be critical in shaping calcium signaling, regulating ATP synthesis and controlling cell death. Calcium uptake occurs through a channel called the uniporter that resides in the inner mitochondrial membrane. Re...

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Bibliographic Details
Main Authors: Molly Plovanich, Roman L Bogorad, Yasemin Sancak, Kimberli J Kamer, Laura Strittmatter, Andrew A Li, Hany S Girgis, Satya Kuchimanchi, Jack De Groot, Lauren Speciner, Nathan Taneja, Jonathan Oshea, Victor Koteliansky, Vamsi K Mootha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3567112?pdf=render

Internet

http://europepmc.org/articles/PMC3567112?pdf=render

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