Auraptene Mitigates Parkinson’s Disease-Like Behavior by Protecting Inhibition of Mitochondrial Respiration and Scavenging Reactive Oxygen Species

Auraptene Mitigates Parkinson’s Disease-Like Behavior by Protecting Inhibition of Mitochondrial Respiration and Scavenging Reactive Oxygen Species

Current therapeutics for Parkinson’s disease (PD) are only effective in providing relief of symptoms such as rigidity, tremors and bradykinesia, and do not exert disease-modifying effects by directly modulating mitochondrial function. Here, we investigated auraptene (AUR) as a potent thera...

Full description

Bibliographic Details
Main Authors: Yunseon Jang, Hyosun Choo, Min Joung Lee, Jeongsu Han, Soo Jeong Kim, Xianshu Ju, Jianchen Cui, Yu Lim Lee, Min Jeong Ryu, Eung Seok Oh, Song-Yi Choi, Woosuk Chung, Gi Ryang Kweon, Jun Young Heo
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
auraptene
dopamine neuron
Parkinson’s disease
neuroprotection
antioxidant
mitochondria
Online Access:https://www.mdpi.com/1422-0067/20/14/3409

Internet

https://www.mdpi.com/1422-0067/20/14/3409

Similar Items