The miRNA199a/SIRT1/P300/Yy1/sST2 signaling axis regulates adverse cardiac remodeling following MI

Abstract Left ventricular remodeling following myocardial infarction (MI) is related to adverse outcome. It has been shown that an up-regulation of plasma soluble ST2 (sST2) levels are associated with lower pre-discharge left ventricular (LV) ejection fraction, adverse cardiovascular outcomes and mo...

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Bibliographic Details
Main Authors: Maria Carmen Asensio-Lopez, Yassine Sassi, Fernando Soler, Maria Josefa Fernandez del Palacio, Domingo Pascual-Figal, Antonio Lax
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82745-9