Substance P Receptor in the Rat Heart and Regulation of Its Expression in Long-Term Diabetes

Substance P Receptor in the Rat Heart and Regulation of Its Expression in Long-Term Diabetes

Substance P (SP) is a neuropeptide engaged in the signal transmission of neural C fibers afferents in the myocardium. The actions of SP in the heart are extensive and they are mediated by the neurokinin 1 receptor (NK1R), a member of the tachykinin subfamily of G-protein coupled receptors. The recep...

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Bibliographic Details
Main Authors: Magdalena Chottova Dvorakova, Eliska Mistrova, Renate Paddenberg, Wolfgang Kummer, Jana Slavikova
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Physiology
Subjects:
neurokinin receptor 1
heart
expression
distribution
diabetes mellitus
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00918/full

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https://www.frontiersin.org/article/10.3389/fphys.2018.00918/full

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