DNA hydrolysing IgG catalytic antibodies: an emerging link between psychoses and autoimmunity

DNA hydrolysing IgG catalytic antibodies: an emerging link between psychoses and autoimmunity

Abstract It is not uncommon to observe autoimmune comorbidities in a significant subset of patients with psychotic disorders, namely schizophrenia (SCZ) and bipolar disorder (BPD). To understand the autoimmune basis, the DNA abyzme activity mediated by serum polyclonal IgG Abs were examined in psych...

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Bibliographic Details
Main Authors: Rajendran Ramesh, Aparna Sundaresh, Ravi Philip Rajkumar, Vir Singh Negi, M. A. Vijayalakshmi, Rajagopal Krishnamoorthy, Ryad Tamouza, Marion Leboyer, A. S. Kamalanathan
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:npj Schizophrenia
Online Access:https://doi.org/10.1038/s41537-021-00143-6

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https://doi.org/10.1038/s41537-021-00143-6

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