Capsaicin displays anti-proliferative activity against human small cell lung cancer in cell culture and nude mice models via the E2F pathway.

Capsaicin displays anti-proliferative activity against human small cell lung cancer in cell culture and nude mice models via the E2F pathway.

Small cell lung cancer (SCLC) is characterized by rapid progression and low survival rates. Therefore, novel therapeutic agents are urgently needed for this disease. Capsaicin, the active ingredient of chilli peppers, displays anti-proliferative activity in prostate and epidermoid cancer in vitro. H...

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Bibliographic Details
Main Authors: Kathleen C Brown, Ted R Witte, W Elaine Hardman, Haitao Luo, Yi C Chen, A Betts Carpenter, Jamie K Lau, Piyali Dasgupta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2857654?pdf=render

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http://europepmc.org/articles/PMC2857654?pdf=render

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