The Neuroprotective Effect of Amitriptyline on Radiation-Induced Impairment of Hippocampal Neurogenesis

The radioprotective effect of amitriptyline, an inhibitor of acid sphingomyelinase (ASMase), on radiation-induced impairment of hippocampal neurogenesis, loss of interneuron, and animal weight changes was investigated in BALB/c mice by immunostaining of biomarkers for cell division (Ki67), immature...

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Bibliographic Details
Main Authors: Yu Rong Guo, Zi Wei Liu, Shuang Peng, Meng Yun Duan, Jing Wei Feng, Wei Feng Wang, Yan Hua Xu, Xi Tang, Xiang Zhi Zhang, Bo Xu Ren, Feng Ru Tang
Format: Article
Language:English
Published: SAGE Publishing 2019-12-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/1559325819895912