Linear superposition and prediction of bacterial promoter activity dynamics in complex conditions.

Bacteria often face complex environments. We asked how gene expression in complex conditions relates to expression in simpler conditions. To address this, we obtained accurate promoter activity dynamical measurements on 94 genes in E. coli in environments made up of all possible combinations of four...

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Bibliographic Details
Main Authors: Daphna Rothschild, Erez Dekel, Jean Hausser, Anat Bren, Guy Aidelberg, Pablo Szekely, Uri Alon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4014397?pdf=render