Age-related oxidative stress confines damage-responsive Bmi1+ cells to perivascular regions in the murine adult heart

Adult progenitor cells reside in specialized microenvironments which maintain their undifferentiated cell state and trigger regenerative responses following injury. Although these environments are well described in several tissues, the cellular components that comprise the cardiac environment where...

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Bibliographic Details
Main Authors: Diego Herrero, Susana Cañón, Guillermo Albericio, Rosa María Carmona, Susana Aguilar, Santos Mañes, Antonio Bernad
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719300758