Common genetic polymorphisms within NFκB-related genes and the risk of developing invasive aspergillosis

Common genetic polymorphisms within NFκB-related genes and the risk of developing invasive aspergillosis

Invasive Aspergillosis (IA) is an opportunistic infection caused by Aspergillus, a ubiquitously present airborne pathogenic mould. A growing number of studies suggest a major host genetic component in disease susceptibility. Here, we evaluated whether 14 single-nucleotide polymorphisms within NFκB1,...

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Bibliographic Details
Main Authors: Carmen Belén Lupiañez, María Teresa Villaescusa, Agostinho Carvalho, Jan Springer, Michaela Lackner, José Manuel Sánchez-Maldonado, Luz María Canet, Cristina Cunha, Juana Segura-Catena, Laura Alcazar-Fuoli, Carlos Solano, Luana Fianchi, Livio Pagano, Leonardo Potenza, José María Aguado, Mario Luppi, Manuel Cuenca-Estrella, Cornelia Lass-Flörl, Hermann Einsele, Lourdes Vázquez, PCRAGA Study Group, Rafael Ríos-Tamayo, Jurgen Loeffler, Manuel Jurado, Juan Sainz
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Microbiology
Subjects:
Hematologic Diseases
Stem Cell Transplantation
Genetic Susceptibility
nfkb pathway
invasive aspergillosis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01243/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01243/full

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