Regulatory role of heme oxygenase-1 in silica-induced lung injury

Regulatory role of heme oxygenase-1 in silica-induced lung injury

Abstract Background Silicosis, a progressive inflammatory lung disease attributed mainly to occupational exposure to silica dust, shows loss of lung function even after cessation of exposure. In addition to conventional evaluation methods such as chest X-ray, computed tomography, and spirometry, we...

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Bibliographic Details
Main Authors: Kentaro Nakashima, Takashi Sato, Suguru Shigemori, Takeshi Shimosato, Masaharu Shinkai, Takeshi Kaneko
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Respiratory Research
Subjects:
Silicosis
Heme oxygenase-1
Antioxidant
Extracellular signal-regulated kinase
Reactive oxygen species
Online Access:http://link.springer.com/article/10.1186/s12931-018-0852-6

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http://link.springer.com/article/10.1186/s12931-018-0852-6

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