Can Genetic Analysis of Putative Blood Alzheimer's Disease Biomarkers Lead to Identification of Susceptibility Loci?

Can Genetic Analysis of Putative Blood Alzheimer's Disease Biomarkers Lead to Identification of Susceptibility Loci?

Although 24 Alzheimer's disease (AD) risk loci have been reliably identified, a large portion of the predicted heritability for AD remains unexplained. It is expected that additional loci of small effect will be identified with an increased sample size. However, the cost of a significant increa...

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Bibliographic Details
Main Authors: Robert C Barber, Nicole R Phillips, Jeffrey L Tilson, Ryan M Huebinger, Shantanu J Shewale, Jessica L Koenig, Jeffrey S Mitchel, Sid E O'Bryant, Stephen C Waring, Ramon Diaz-Arrastia, Scott Chasse, Kirk C Wilhelmsen, Alzheimer’s Disease Neuroimaging Initiative, Texas Alzheimer’s Research and Care Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4666664?pdf=render

Internet

http://europepmc.org/articles/PMC4666664?pdf=render

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