Selective antagonism of cJun for cancer therapy

Selective antagonism of cJun for cancer therapy

Abstract The activator protein-1 (AP-1) family of transcription factors modulate a diverse range of cellular signalling pathways into outputs which can be oncogenic or anti-oncogenic. The transcription of relevant genes is controlled by the cellular context, and in particular by the dimeric composit...

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Bibliographic Details
Main Authors: Andrew Brennan, James T. Leech, Neil M. Kad, Jody M. Mason
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
c-Jun
Activator Protein-1
transcriptional regulator
basic leucine zipper
cancer
peptides
Online Access:http://link.springer.com/article/10.1186/s13046-020-01686-9

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http://link.springer.com/article/10.1186/s13046-020-01686-9

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