circCUL2 regulates gastric cancer malignant transformation and cisplatin resistance by modulating autophagy activation via miR-142-3p/ROCK2

circCUL2 regulates gastric cancer malignant transformation and cisplatin resistance by modulating autophagy activation via miR-142-3p/ROCK2

Abstract Background Circular RNAs (circRNAs) are a class of noncoding RNAs (ncRNAs) and can modulate gene expression by binding to miRNAs; further, circRNAs have been shown to participate in several pathological processes. However, the expression and biological function of circCUL2 in gastric cancer...

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Bibliographic Details
Main Authors: Lei Peng, Huaiming Sang, Shuchun Wei, Yuanyuan Li, Duochen Jin, Xudong Zhu, Xuan Li, Yini Dang, Guoxin Zhang
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Molecular Cancer
Subjects:
circCUL2
miR-142-3p
ROCK2
Gastric cancer
Cisplatin resistance
Autophagy
Online Access:http://link.springer.com/article/10.1186/s12943-020-01270-x

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http://link.springer.com/article/10.1186/s12943-020-01270-x

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