Clinical oxidative stress during leprosy multidrug therapy: impact of dapsone oxidation.

This study aims to assess the oxidative stress in leprosy patients under multidrug therapy (MDT; dapsone, clofazimine and rifampicin), evaluating the nitric oxide (NO) concentration, catalase (CAT) and superoxide dismutase (SOD) activities, glutathione (GSH) levels, total antioxidant capacity, lipid...

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Main Authors: Taysa Ribeiro Schalcher, Rosivaldo S Borges, Michael D Coleman, João Batista Júnior, Claudio G Salgado, Jose Luiz F Vieira, Pedro R T Romão, Fabio R Oliveira, Marta Chagas Monteiro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3899049?pdf=render