Explaining the variation in the attained power of a stepped-wedge trial with unequal cluster sizes

Explaining the variation in the attained power of a stepped-wedge trial with unequal cluster sizes

Abstract Background In a cross-sectional stepped-wedge trial with unequal cluster sizes, attained power in the trial depends on the realized allocation of the clusters. This attained power may differ from the expected power calculated using standard formulae by averaging the attained powers over all...

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Bibliographic Details
Main Authors: Yongdong Ouyang, Mohammad Ehsanul Karim, Paul Gustafson, Thalia S. Field, Hubert Wong
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Medical Research Methodology
Subjects:
Cluster randomized trial
Power distribution
Treatment-time period correlation
Treatment group imbalance
Online Access:http://link.springer.com/article/10.1186/s12874-020-01036-5

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http://link.springer.com/article/10.1186/s12874-020-01036-5

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