Cooperation of Hsp70 and Hsp100 chaperone machines in protein disaggregation

Cooperation of Hsp70 and Hsp100 chaperone machines in protein disaggregation

Unicellular and sessile organisms are particularly exposed to environmental stress such as heat shock causing accumulation and aggregation of misfolded protein species. To counteract protein aggregation, bacteria, fungi and plants encode a bi-chaperone system composed of ATP-dependent Hsp70 and hexa...

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Bibliographic Details
Main Authors: Axel eMogk, Eva eKummer, Bernd eBukau
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
Hsp70
Chaperone
Hsp100
AAA+ proteins
Protein Disaggregation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00022/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00022/full

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