Modulation of Gut Microbiota by Low Methoxyl Pectin Attenuates Type 1 Diabetes in Non-obese Diabetic Mice

Modulation of Gut Microbiota by Low Methoxyl Pectin Attenuates Type 1 Diabetes in Non-obese Diabetic Mice

Intestinal homeostasis underpins the development of type 1 diabetes (T1D), and dietary manipulations to enhance intestinal homeostasis have been proposed to prevent T1D. The current study aimed to investigate the efficacy of supplementing a novel specific low-methoxyl pectin (LMP) dietary fiber in p...

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Bibliographic Details
Main Authors: Chengfei Wu, Li-Long Pan, Wenying Niu, Xin Fang, Wenjie Liang, Jiahong Li, Hongli Li, Xiaohua Pan, Wei Chen, Hao Zhang, Jonathan R. T. Lakey, Birgitta Agerberth, Paul de Vos, Jia Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
low-methoxyl pectin
autoimmune diabetes
immunomodulation
gut microbiota
intestinal homeostasis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01733/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01733/full

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