Early-life Social Isolation Impairs the Gonadotropin-Inhibitory Hormone Neuronal Activity and Serotonergic System in Male Rats

Early-life Social Isolation Impairs the Gonadotropin-Inhibitory Hormone Neuronal Activity and Serotonergic System in Male Rats

Social isolation in early life deregulates the serotonergic system of the brain, compromising reproductive function. Gonadotropin-inhibitory hormone (GnIH) neurons in the dorsomedial hypothalamic nucleus are critical to the inhibitory regulation of gonadotropin-releasing hormone neuronal activity in...

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Bibliographic Details
Main Authors: Tomoko eSoga, Chuin Hau eTeo, kai Lin eCham, Marshita eIdris, Ishwar S Parhar
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Endocrinology
Subjects:
Serotonin
GnRH
social stress
dorsal raphe
dorsomedial hypothalamus
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00172/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00172/full

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