Molecular Mechanism of the Antiproliferative Activity of Short Immunostimulating dsRNA
Small double-stranded RNAs with certain sequence motifs are able to interact with pattern-recognition receptors and activate the innate immune system. Recently, we identified a set of short double-stranded 19-bp RNA molecules with 3-nucleotide 3′-overhangs that exhibited pronounced antiproliferative...
Main Authors: | Mikhail I. Zharkov, Marina A. Zenkova, Valentin V. Vlassov, Elena L. Chernolovskaya |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-12-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fonc.2019.01454/full |
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