Molecular predictors of response to tyrosine kinase inhibitors in patients with Non-Small-Cell Lung Cancer

Molecular predictors of response to tyrosine kinase inhibitors in patients with Non-Small-Cell Lung Cancer

<p>Abstract</p> <p>Introduction</p> <p>Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have become a treatment option in non-small-cell lung cancer (NSCLC) patients. However, despite their use in this disease, a significant number of patients w...

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Bibliographic Details
Main Authors: Murray Samuel, Karavasilis Vasilios, Bobos Mattheos, Razis Evangelia, Papadopoulos Savvas, Christodoulou Christos, Kosmidis Paris, Fountzilas George
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Predictive
Somatic mutation
EGFR
Gefitinib
Erlotinib
Response
Online Access:http://www.jeccr.com/content/31/1/77

Internet

http://www.jeccr.com/content/31/1/77

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