Producing Novel Fibrinolytic Isoindolinone Derivatives in Marine Fungus Stachybotrys longispora FG216 by the Rational Supply of Amino Compounds According to Its Biosynthesis Pathway

Producing Novel Fibrinolytic Isoindolinone Derivatives in Marine Fungus Stachybotrys longispora FG216 by the Rational Supply of Amino Compounds According to Its Biosynthesis Pathway

Many fungi in the Stachybotrys genus can produce various isoindolinone derivatives. These compounds are formed by a spontaneous reaction between a phthalic aldehyde precursor and an ammonium ion or amino compounds. In this study, we suggested the isoindolinone biosynthetic gene cluster in Stachybotr...

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Bibliographic Details
Main Authors: Ying Yin, Qiang Fu, Wenhui Wu, Menghao Cai, Xiangshan Zhou, Yuanxing Zhang
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Marine Drugs
Subjects:
Stachybotrys
isoindolinone biosynthesis
genome mining
amino compound
fibrinolytic activity
Online Access:https://www.mdpi.com/1660-3397/15/7/214

Internet

https://www.mdpi.com/1660-3397/15/7/214

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