Upregulation of miR-196b confers a poor prognosis in glioblastoma patients via inducing a proliferative phenotype.

PURPOSE: To explore the expression pattern, prognostic value and functional role of miR-196b in glioblastoma (GBM) patients using large cohorts. EXPERIMENTAL DESIGN: MiR-196b expression was measured using the Human v2.0 miRNA Expression BeadChip (Illumina) in 198 frozen glioma tissues. The expressio...

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Bibliographic Details
Main Authors: Ruimin Ma, Wei Yan, Guojun Zhang, Hong Lv, Zhizhong Liu, Fang Fang, Wei Zhang, Junxia Zhang, Tao Tao, Yongping You, Tao Jiang, Xixiong Kang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3378534?pdf=render