Synthesis, biological evaluation, molecular docking and in silico ADMET screening studies of novel isoxazoline derivatives from acridone
A series of new acridone derivatives from isoxazoline (2a-l) were synthesized via 1,3-dipolar cycloaddition reaction between a variety of aryl nitrile oxides and N-allyl acridones using simple and efficient methods. This is the first ever green protocol to synthesize novel isoxazolines derivatives f...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-04-01
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Series: | Arabian Journal of Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535221000721 |