Achieving Metabolic Flux Analysis for S. cerevisiae at a Genome-Scale: Challenges, Requirements, and Considerations

Recent advances in 13C-Metabolic flux analysis (13C-MFA) have increased its capability to accurately resolve fluxes using a genome-scale model with narrow confidence intervals without pre-judging the activity or inactivity of alternate metabolic pathways. However, the necessary precautions, computat...

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Bibliographic Details
Main Authors: Saratram Gopalakrishnan, Costas D. Maranas
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:Metabolites
Subjects:
Online Access:http://www.mdpi.com/2218-1989/5/3/521