Improved DNA extraction technique from clot for the diagnosis of Chagas disease.

<h4>Background</h4>The detection of Trypanosoma cruzi genetic material in clinical samples is considered an important diagnostic tool for Chagas disease. We have previously demonstrated that PCR using clot samples yields greater sensitivity than either buffy coat or whole blood samples....

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Bibliographic Details
Main Authors: Holger Mayta, Yomara K Romero, Alejandra Pando, Manuela Verastegui, Freddy Tinajeros, Ricardo Bozo, Josephine Henderson-Frost, Rony Colanzi, Jorge Flores, Richard Lerner, Caryn Bern, Robert H Gilman, Chagas Working Group in Perú and Bolivia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007024