Helicobacter pylori-controlled c-Abl localization promotes cell migration and limits apoptosis

Helicobacter pylori-controlled c-Abl localization promotes cell migration and limits apoptosis

Abstract Background Deregulated c-Abl activity has been intensively studied in a variety of solid tumors and leukemia. The class-I carcinogen Helicobacter pylori (Hp) activates the non-receptor tyrosine kinase c-Abl to phosphorylate the oncoprotein cytotoxin-associated gene A (CagA). The role of c-A...

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Bibliographic Details
Main Authors: Gernot Posselt, Maria Wiesauer, Bianca E. Chichirau, Daniela Engler, Linda M. Krisch, Gabriele Gadermaier, Peter Briza, Sabine Schneider, Francesco Boccellato, Thomas F. Meyer, Cornelia Hauser-Kronberger, Daniel Neureiter, Anne Müller, Silja Wessler
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Cell Communication and Signaling
Subjects:
C-Abl
Apoptosis
Cancer
Gastritis
Helicobacter pylori
Motility
Online Access:http://link.springer.com/article/10.1186/s12964-019-0323-9

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http://link.springer.com/article/10.1186/s12964-019-0323-9

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