Targeting Mitochondrial Oxidative Stress to Mitigate UV-Induced Skin Damage

Targeting Mitochondrial Oxidative Stress to Mitigate UV-Induced Skin Damage

Unmitigated UV radiation (UVR) induces skin photoaging and multiple forms of cutaneous carcinoma by complex pathways that include those mediated by UV-induced reactive oxygen species (ROS). Upon UVR exposure, a cascade of events is induced that overwhelms the skin’s natural antioxidant defenses and...

Full description

Bibliographic Details
Main Authors: Rhonda M. Brand, Peter Wipf, Austin Durham, Michael W. Epperly, Joel S. Greenberger, Louis D. Falo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Pharmacology
Subjects:
oxidative stress
mitochondria
photoaging
photocarcinogenesis
ROS
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00920/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00920/full

Similar Items