Preventive and therapeutic effects of JM-20 on paclitaxel-evoked painful peripheral neuropathy in rats

Preventive and therapeutic effects of JM-20 on paclitaxel-evoked painful peripheral neuropathy in rats

Context: JM-20 is a hybrid synthetic molecule, which is based on a multimodal drug design paradigm for cerebrovascular disease. In addition to its neuroprotective effects, JM-20 also decreased sciatic nerve chronic constriction injury (CCI)-induced mechanical hypersensitivity in rats. JM-20 has a st...

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Bibliographic Details
Main Authors: Bárbara B. Garrido-Suárez, Gabino Garrido, Addis Bellma Menéndez, Guillermo Aparicio, Odalys Valdés, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, René Delgado-Hernández
Format: Article
Language:English
Published: Academic Association of Pharmaceutical Sciences from Antofagasta (ASOCIFA) 2021-03-01
Series:Journal of Pharmacy & Pharmacognosy Research
Subjects:
chemotherapy
jm-20
mitochondria
neuropathic pain
neuroprotection
Online Access:https://jppres.com/jppres/pdf/vol9/jppres20.970_9.2.165.pdf

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https://jppres.com/jppres/pdf/vol9/jppres20.970_9.2.165.pdf

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