Iron and glutathione at the crossroad of redox metabolism in neurons

Neurons, as non-dividing cells, encounter a myriad of stressful conditions throughout their lifespan. In particular, there is increasing evidence that iron progressively accumulates in the brain with age and that iron-induced oxidative stress is the cause of several forms of neurodegeneration. Here,...

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Bibliographic Details
Main Authors: PAULA ARACENA, PABLA AGUIRRE, PABLO MUÑOZ, MARCO T NÚÑEZ
Format: Article
Language:English
Published: BMC 2006-01-01
Series:Biological Research
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000100017