Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations

Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations

Recent studies suggest key roles of RNA in DNA double-strand breaks repair. Here the authors identify the helicase senataxin to be involved in DNA repair and resolve RNA:DNA hybrids forming at DNA double-strand breaks.

Bibliographic Details
Main Authors: Sarah Cohen, Nadine Puget, Yea-Lih Lin, Thomas Clouaire, Marion Aguirrebengoa, Vincent Rocher, Philippe Pasero, Yvan Canitrot, Gaëlle Legube
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-02894-w

Internet

https://doi.org/10.1038/s41467-018-02894-w

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