Characterization and functional analysis of cathelicidin-MH, a novel frog-derived peptide with anti-septicemic properties

Characterization and functional analysis of cathelicidin-MH, a novel frog-derived peptide with anti-septicemic properties

Antimicrobial peptides form part of the innate immune response and play a vital role in host defense against pathogens. Here we report a new antimicrobial peptide belonging to the cathelicidin family, cathelicidin-MH (cath-MH), from the skin of Microhyla heymonsivogt frog. Cath-MH has a single α-hel...

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Bibliographic Details
Main Authors: Jinwei Chai, Xin Chen, Tiaofei Ye, Baishuang Zeng, Qingye Zeng, Jiena Wu, Barbora Kascakova, Larissa Almeida Martins, Tatyana Prudnikova, Ivana Kuta Smatanova, Michail Kotsyfakis, Xueqing Xu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
antimicrobial peptides
cathelicidin
microhyla heymonsivogt
inflammation
sepsis
Online Access:https://elifesciences.org/articles/64411

Internet

https://elifesciences.org/articles/64411

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