Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines.

Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines.

To improve cancer therapy, it is critical to target metastasizing cells. Circulating tumor cells (CTCs) are rare cells found in the blood of patients with solid tumors and may play a key role in cancer dissemination. Uncovering CTC phenotypes offers a potential avenue to inform treatment. However, C...

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Bibliographic Details
Main Authors: Ashley A Powell, Amirali H Talasaz, Haiyu Zhang, Marc A Coram, Anupama Reddy, Glenn Deng, Melinda L Telli, Ranjana H Advani, Robert W Carlson, Joseph A Mollick, Shruti Sheth, Allison W Kurian, James M Ford, Frank E Stockdale, Stephen R Quake, R Fabian Pease, Michael N Mindrinos, Gyan Bhanot, Shanaz H Dairkee, Ronald W Davis, Stefanie S Jeffrey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3346739?pdf=render

Internet

http://europepmc.org/articles/PMC3346739?pdf=render

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