Endothelial Wnts control mammary epithelial patterning via fibroblast signaling

Endothelial Wnts control mammary epithelial patterning via fibroblast signaling

Summary: Endothelial and fibroblast niches are crucial for epithelial organs. How these heterotypic cells interact is of great interest. In this study, we reveal an axis of signaling in which fibroblasts relay Wnt signals from the endothelial niche to organize epithelial patterning. We generate an A...

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Bibliographic Details
Main Authors: Jingqiang Wang, Wenqian Song, Ruikai Yang, Chao Li, Ting Wu, Xiao Bing Dong, Bin Zhou, Xizhi Guo, Jianfeng Chen, Zhiyong Liu, Qing Cissy Yu, Wen Li, Junfen Fu, Yi Arial Zeng
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Cell Reports
Subjects:
Wnt/β-catenin signaling
Axin2
endothelial cells
fibroblasts
niche
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721002114

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http://www.sciencedirect.com/science/article/pii/S2211124721002114

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